Eficácia anti-helmíntica de dois princípios ativos no controle da verminose ovina
A hookworm is a disease caused by nematodes. Helminths that cause more harm in the chain are the Trichostrongylidae family (Haemonchus contortus and Trichostrongylus ssp.) And the Strongyloididae family (Strongyloides papillosus). It has constituted a major problem for the sheep industry, due to mor...
| Autor principal: | Stevale, Gustavo Tavares de Souza |
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| Formato: | Trabalho de Conclusão de Curso (Graduação) |
| Idioma: | Português |
| Publicado em: |
Universidade Tecnológica Federal do Paraná
2020
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| Assuntos: | |
| Acesso em linha: |
http://repositorio.utfpr.edu.br/jspui/handle/1/11342 |
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| Resumo: |
A hookworm is a disease caused by nematodes. Helminths that cause more harm in the chain are the Trichostrongylidae family (Haemonchus contortus and Trichostrongylus ssp.) And the Strongyloididae family (Strongyloides papillosus). It has constituted a major problem for the sheep industry, due to mortality and sheep lost productivity. Thus the control of this disease is of paramount importance for the economic viability of the activity and success of the productive chain of sheep meat. The objective of this study is to assess the action of two active principles in worms control in naturally infected sheep with Haemonchus spp., Trichostrogylus spp and S. papillosus as the anthelmintic action of the active principles and the anthelmintic resistance acquired from nematodes. The experiment will take place over a period of 28 days and will be used 21 animals of both ½Dorper x ½Santa Inês with ages and different weight. An egg count per gram of feces examination will be made of each animal to determine the distribution of animals in three groups according to their average. Collections were made from feces and blood for the eggs tests execution per gram of feces (OPG), hematocrit, total plasma protein and faecal cultures. Based on the values found for OPG it was determined the efficiency of the two anthelmintic used. The animals were divided into three treatments, and the Control group that was not submitted to anthelmintic intervention. Levamisol group that received Ripecoll [marca registrada] the base Levamisol hydrochloride 5% in the dose recommended by the manufacturer. And Moxidectin group receiving Cydectin [marca registrada] moxidectin 1%, also administered according to the manufacturer. The helminth species found by examining stool cultures were prevalently Haemonchus contortus and Trichostrongylus colubriformis. The results of hematocrit tests, total plasma protein and Famacha showed no statistical difference between the groups (P> 0.05) and remained within the normal range for the species. The OPG values found no significant difference (P> 0.05) except for the value found on day 14 for Levamisol group that had the lowest average (775). The anthelmintics showed no effectiveness in controlling sheep hookworm: Levamisol 72% and Moxidectin 28%, below the minimum level (80%), then classified as ineffective medication. Both tested active ingredients had to be ineffective in controlling sheep helminth. |
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